Gastrointestinal Endoscopy
Volume 62, Issue 4 , Pages 488-498 , October 2005

Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett's esophagus: international, partially blinded, randomized phase III trial

Received 24 November 2004 ,Accepted 13 June 2005.

References 

  1. Barrett NR. Chronic peptic ulcer of the oesophagus and ‘esophagitis.’. Br J Surg. 1950;38:175–182
  2. Allison PR, Johnstone AS. The oesophagus lined with gastric mucous membrane. Thorax. 1953;8:87–101
  3. Reid BJ. Barrett's esophagus and esophageal carcinoma. Gastroenterol Clin of North Am. 1991;20:817–834
  4. Stein HJ, Siewert JR. Barrett's esophagus: pathogenesis, epidemiology, functional abnormalities, malignant degeneration, and surgical management. Dysphagia. 1993;8:276–288
  5. Spechler SJ, Goyal RK. Barrett's esophagus. N Engl J Med. 1986;315:362–371
  6. Haggitt RC. Barrett's esophagus, dysplasia, and adenocarcinoma. Hum Pathol. 1994;25:982–993
  7. Shaheen NJ, Crosby MA, Bozymski EM. Is there publication bias in the reporting of cancer risk of Barrett's esophagus?. Gastroenterology. 2000;119:333–338
  8. Hameeteman W, Tytgat GN, Houthoff HJ, et al. Barrett's esophagus: development of dysplasia and adenocarcinoma. Gastroenterology. 1989;96:1249–1256
  9. Cameron AJ, Lomboy CT, Pera M, et al. Adenocarcinoma of the esophagogastric junction and Barrett's esophagus. Gastroenterology. 1995;109:1541–1546
  10. Hamilton SR, Smith RR. The relationship between columnar epithelial dysplasia and invasive adenocarcinoma arising in Barrett's esophagus. Am J Clin Pathol. 1987;87:301–312
  11. Weston AP, Sharma P, Topalovski M, et al. Long-term follow-up of Barrett's high-grade dysplasia. Am J Gastroenterol. 2000;95:1888–1893
  12. Rice TW, Falk GW, Achkar E, et al. Surgical management of high-grade dysplasia in Barrett's esophagus. Am J Gastroenterol. 1993;88:1832–1836
  13. Nigro JJ, Hagen JA, DeMeester TR, et al. Occult esophageal adenocarcinoma: extent of disease and implications for effective therapy. Ann Surg. 1999;230:433–440
  14. Heitmiller RF, Redmond M, Hamilton SR. Barrett's esophagus with high-grade dysplasia. An indication for prophylactic esophagectomy. Ann Surg. 1996;224:66–71
  15. Pera M, Trastek VF, Carpenter HA, et al. Barrett's esophagus with high-grade dysplasia: an indication for esophagectomy?. Ann Thorac Surg. 1992;54:199–204
  16. Altorki NK, Sunagawa M, Little AG, et al. High-grade dysplasia in the columnar-lined esophagus. Am J Surg. 1991;161:97–99
  17. Streitz JM Jr, Ellis H Jr. Barrett's esophagus. In: Shields TW, editor. General thoracic surgery. vol. 2. 4th ed. Baltimore: Williams and Wilkins, Malvern; 1994. p. 1612-21.
  18. Begg CB, Cramer LD, Hoskins WJ, et al. Impact of hospital volume on operative mortality for major cancer surgery. JAMA. 1998;280:1747–1751
  19. Schnell TG, Sontag SJ, Chejfec G, et al. Long-term nonsurgical management of Barrett's esophagus with high-grade dysplasia. Gastroenterology. 2001;120:1607–1619
  20. Reid BJ, Weinstein WM, Lewin KJ, et al. Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions. Gastroenterology. 1988;94:81–90
  21. Dulai GS, Jensen DM, Cortina G, et al. Randomized trial of argon plasma coagulation vs. multipolar electrocoagulation for ablation of Barrett's esophagus. Gastrointest Endosc. 2005;61:232–240
  22. Sampliner RE, Faigel D, Fennerty B, et al. Effective and safe endoscopic reversal of nondysplastic Barrett's esophagus with thermal electrocoagulation combined with high-dose acid inhibition: a multicenter study. Gastrointest Endosc. 2001;53:554–558
  23. Berenson MM, Johnson TD, Markowitz NR, et al. Restoration of squamous mucosa after ablation of Barrett's esophagus epithelium. Gastroenterology. 1993;104:1686–1691
  24. Sampliner RE, Hixson LJ, Fennerty MB, et al. Regression of Barrett's esophagus by laser ablation in an antacid environment. Dig Dis Sci. 1993;38:365–368
  25. Gossner L, May A, Stolte M, et al. KTP laser destruction of dysplasia and early cancer in columnar-lined Barrett's esophagus. Gastrointest Endosc. 1999;49:8–12
  26. Weston AP, Sharma P. Neodymium:yttrium-aluminum garnet contact laser ablation of Barrett's high grade dysplasia and early adenocarcinoma. Am J Gastroenterol. 2002;97:2998–3006
  27. Barham CP, Jones RL, Biddlesone LR, et al. Photothermal laser ablation of Barrett's oesophagus: endoscopic and histological evidence of squamous re-epithelialisation. Gut. 1997;41:281–284
  28. Salo JA, Salminen JT, Kiviluoto TA, et al. Treatment of Barrett's esophagus by endoscopic laser ablation and antireflux surgery. Ann Surg. 1998;227:40–44
  29. Montes CG, Brandalise A, Deliza R, et al. Antireflux surgery followed by bipolar electrocoagulation in the treatment of Barrett's esophagus. Gastrointest Endosc. 1999;50:173–177
  30. Overholt BF, Panjehpour M. Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa and treatment of superficial esophageal cancer. Gastrointest Endosc. 1995;42:64–69
  31. Laukka MA, Wang KK. Initial results using low-dose photodynamic therapy in the treatment of Barrett's esophagus. Gastrointest Endosc. 1995;42:96–98
  32. Overholt BF, Panjehpour M, Haydek JM. Photodynamic therapy for Barrett's esophagus: follow-up in 100 patients. Gastrointest Endosc. 1999;49:1–7
  33. Overholt BF, Panjehpour M. Photodynamic therapy techniques for ablation of Barrett's esophagus. Techniques in Gastrointest Endosc. 2000;2:203–208
  34. Levine DS, Reid BJ. Endoscopic biopsy technique for acquiring larger mucosal samples. Gastrointest Endosc. 1991;37:332–337
  35. Overholt BF, Panjehpour M, Teffetellar E, et al. Photodynamic therapy for treatment of early adenocarcinoma in Barrett's esophagus. Gastrointest Endosc. 1993;39:73–76
  36. Panjehpour M, Overholt BF, Haydek JM, et al. Results of photodynamic therapy for ablation of dysplasia and early cancer in Barrett's esophagus and effect of oral steroids on stricture formation. Am J Gastroenterol. 2000;95:2177–2184
  37. Wang KK. Photodynamic therapy of Barrett's esophagus. Gastrointest Endosc Clin N Am. 2000;10:409–419
  38. Wolfson HC, Hemminger LL, Wallace MB, et al. Clinical experience of patients undergoing photodynamic therapy for Barrett's dysplasia or cancer. Aliment Pharmacol Ther. 2004;20:1125–1131
  39. Overholt BF, Panjehpour M, Halberg D. Photodynamic therapy for Barrett's esophagus with dysplasia and early carcinoma: long term results. Gastrointest Endosc. 2003;58:183–188
  40. Barr H, Shepherd NA, Dix A, et al. Eradication of high-grade dysplasia in columnar-lined (Barrett's) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet. 1996;348:584–585
  41. Gossner L, Stolte M, Sroka R, et al. Photodynamic ablation of high-grade dysplasia and early cancer in Barrett's esophagus by means of 5-aminolevulinc acid. Gastroenterol. 1998;114:448–455
  42. Ackroyd R, Brown NJ, Davis MF, et al. Photodynamic therapy for dysplastic Barrett's oesophagus: a prospective, double blind, randomised, placebo controlled trial. Gut. 2000;47:612–617
  43. Ackroyd R, Kelty CJ, Brown NJ, et al. Eradication of dysplastic Barrett's oesophagus using photodynamic therapy: long term follow-up. Endoscopy. 2003;35:496–501
  44. Ortner M-A, Zumbusch K, Liebetruth J, et al. Is topical 5-aminolevulinc acid adequate for photodynamic therapy in Barrett's esophagus? A pilot study. Endoscopy. 2002;34:611–616
  45. Sharma P, Jaffee PE, Bhattacharyya A, et al. Laser and multipolar electrocoagulation ablation of early Barrett's adenocarcinoma: long term follow-up. Gastrointest Endosc. 1999;49:442–446
  46. Attwood SEA, Lewis CJ, Caplin S, Hemming K, Armstrong G. Argon beam plasma coagulation as therapy for high-grade dysplasia in Barrett's esophagus. Clin Gastroenterol and Hepatology 2003;1:258-263.
  47. Van Laethem J-L, Cremer M, Peny MO, et al. Eradication of Barrett's mucosa with argon plasma coagulation and acid suppression: immediate and mid term results. Gut. 1998;43:747–751
  48. Pereira-Lima JC, Busnello JV, Saul C, et al. High power setting argon plasma coagulation for the eradication of Barrett's esophagus. Am J Gastroenterol. 2000;95:1661–1668
  49. Kahaleh M, Van Laethem J-L, Nagy N, et al. Long-term follow-up and factors predictive of recurrence in Barrett's esophagus treated by argon plasma coagulation and acid suppression. Endoscopy. 2002;34:950–955

 See CME section; p. 584.

PII: S0016-5107(05)02349-7

doi: 10.1016/j.gie.2005.06.047

Gastrointestinal Endoscopy
Volume 62, Issue 4 , Pages 488-498 , October 2005