Endoscopic closure of a gastrojejunal anastomotic leak (with video)

 CommentaryHistorically, the term glue referred only to protein colloids prepared from animal tissues, but today, the meaning has been expanded to refer to any fluid adhesive. Bergel first reported the use of fibrin as a biologic adhesive in 1909. When the 2 components of fibrin glue, fibrinogen and thrombin, come into contact with each other, the final stage of coagulation is initiated and fibrin is formed, acting as a sealant, hemostatic agent, and adhesive. To further ensure a good apposition of tissue, the authors also employed mechanical clips; use of such a “belt and suspenders” approach is prudent, for who wants their pants to fall down at an inconvenient time?Lawrence J. Brandt, MDAssociate Editor for Focal Points

PII: S0016-5107(07)02189-X

doi: 10.1016/j.gie.2007.06.037

© 2007 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.