Gastrointestinal Endoscopy
Volume 70, Issue 2 , Pages 322-330 , August 2009

Reliability and accuracy of the endoscopic appearance in the identification of aberrant crypt foci

Received 30 June 2008 ,Accepted 13 December 2008.

References 

  1. Gupta AK, Pretlow TP, Schoen RE. Aberrant crypt foci: what we know and what we need to know. Clin Gastroenterol Hepatol. 2007;5:526–533
  2. Bird RP. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett. 1987;37:147–151
  3. Fenoglio-Preiser CM, Noffsinger A. Aberrant crypt foci: a review. Toxicol Pathol. 1999;27:632–642
  4. Corpet DE, Tache S. Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. Nutr Cancer. 2002;43:1–21
  5. Pretlow TP, Barrow BJ, Ashton WS, et al. Aberrant crypts: putative preneoplastic foci in human colonic mucosa. Cancer Res. 1991;51:1564–1567
  6. Yokota T, Sugano K, Kondo H, et al. Detection of aberrant crypt foci by magnifying colonoscopy. Gastrointest Endosc. 1997;46:61–65
  7. Takayama T, Katsuki S, Takahashi Y, et al. Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med. 1998;339:1277–1284
  8. Hurlstone DP, Karajeh M, Sanders DS, et al. Rectal aberrant crypt foci identified using high-magnification-chromoscopic colonoscopy: biomarkers for flat and depressed neoplasia. Am J Gastroenterol. 2005;100:1283–1289
  9. Adler DG, Gostout CJ, Sorbi D, et al. Endoscopic identification and quantification of aberrant crypt foci in the human colon. Gastrointest Endosc. 2002;56:657–662
  10. Seike K, Koda K, Oda K, et al. Assessment of rectal aberrant crypt foci by standard chromoscopy and its predictive value for colonic advanced neoplasms. Am J Gastroenterol. 2006;101:1362–1369
  11. Rudolph RE, Dominitz JA, Lampe JW, et al. Risk factors for colorectal cancer in relation to number and size of aberrant crypt foci in humans. Cancer Epidemiol Biomarkers Prev. 2005;14:605–608
  12. Schoen RE, Mutch M, Rall C, et al. The natural history of aberrant crypt foci. Gastrointest Endosc. 2008;67:1097–1102
  13. Mutch M, Schoen RE, Fleshman JW, et al. Prevalence and risk factors for aberrant crypt foci: an ancillary study to the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. [abstract] Gastroenterology. 2007;132:20
  14. Prorok PC, Andriole GL, Bresalier RS, et al. Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin Trials. 2000;21(Suppl):273S–309S
  15. Di Gregorio C, Losi L, Fante R, et al. Histology of aberrant crypt foci in the human colon. Histopathology. 1997;30:328–334
  16. Shpitz B, Bomstein Y, Mekori Y, et al. Aberrant crypt foci in human colons: distribution and histomorphologic characteristics. Hum Pathol. 1998;29:469–475
  17. Lau JY, Sung JJ, Chan AC, et al. Stigmata of hemorrhage in bleeding peptic ulcers: an interobserver agreement study among international experts. Gastrointest Endosc. 1997;46:33–36
  18. Curvers W, Baak L, Kiesslich R, et al. Chromoendoscopy and narrow-band imaging compared with high-resolution magnification endoscopy in Barrett's esophagus. Gastroenterology. 2008;134:670–679

 DISCLOSURE: The following authors received research support for this study from the National Cancer Institute: A. K. Gupta, P. Pinsky, C. Rall, M. Mutch, S. Dry, D. Seligson, R. E. Schoen.

 Presented at Digestive Disease Week, May 17-22, 2008, San Diego, CA (Gastroenterology 2008;134:A445-6).

 If you want to chat with an author of this article, you may contact him at rschoen@pitt.edu.

PII: S0016-5107(08)03180-5

doi: 10.1016/j.gie.2008.12.060

Gastrointestinal Endoscopy
Volume 70, Issue 2 , Pages 322-330 , August 2009

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