Gastrointestinal Endoscopy
Volume 70, Issue 6 , Pages 1231-1237 , December 2009

Endoscopic injection of skeletal muscle–derived cells augments gut smooth muscle sphincter function: implications for a novel therapeutic approach

Received 24 August 2008 ,Accepted 1 May 2009.

References 

  1. FDA preliminary public health notification: recall of Boston Scientific Enteryx procedure kits and Enteryx injector single packs for the treatment of gastroesophageal reflux disease (GERD). Available at: http://www.fda.gov/cdrh/safety/101405-enteryx.html. Accessed October 14, 2005.
  2. Smaldone MC, Chancellor MB. Muscle derived stem cell therapy for stress urinary incontinence. World J Urol. 2008;26:327–332
  3. Carr LK, Steele D, Steele S, et al. 1-year follow-up of autologous muscle-derived stem cell injection pilot study to treat stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct. 2008;19:881–883
  4. Jankowski RJ, Haluszczak C, Trucco M, et al. Flow cytometric characterization of myogenic cell populations obtained via the preplate technique: potential for rapid isolation of muscle-derived stem cells. Hum Gene Ther. 2001;12:619–628
  5. Jankowski RJ, Huard J. Establishing reliable criteria for isolating myogenic cell fractions with stem cell properties and enhanced regenerative capacity. Blood Cells Mol Dis. 2004;32:24–33
  6. Strasser H, Marksteiner R, Margreiter E, et al. Transurethral ultrasonography-guided injection of adult autologous stem cells versus transurethral endoscopic injection of collagen in treatment of urinary incontinence. World J Urol. 2007;25:385–392
  7. Kim YT, Kim DK, Jankowski RJ, et al. Human muscle-derived cell injection in a rat model of stress urinary incontinence. Muscle Nerve. 2007;36:391–393
  8. Furuta A, Jankowski RJ, Pruchnic R, et al. The promise of stem cell therapy to restore urethral sphincter function. Curr Urol Rep. 2007;8:373–378
  9. Furuta A, Jankowski RJ, Pruchnic R, et al. The potential of muscle-derived stem cells for stress urinary incontinence. Expert Opin Biol Ther. 2007;7:1483–1486
  10. Furuta A, Jankowski RJ, Honda M, et al. State of the art of where we are at using stem cells for stress urinary incontinence. Neurourol Urodyn. 2007;26:966–971
  11. Feki A, Faltin DL, Lei T, et al. Sphincter incontinence: is regenerative medicine the best alternative to restore urinary or anal sphincter function?. Int J Biochem Cell Biol. 2007;39:678–684
  12. Peyromaure M, Sebe P, Praud C, et al. Fate of implanted syngenic muscle precursor cells in striated urethral sphincter of female rats: perspectives for treatment of urinary incontinence. Urology. 2004;64:1037–1041
  13. Chermansky CJ, Tarin T, Kwon DD, et al. Intraurethral muscle-derived cell injections increase leak point pressure in a rat model of intrinsic sphincter deficiency. Urology. 2004;63:780–785
  14. Lee JY, Cannon TW, Pruchnic R, et al. The effects of periurethral muscle-derived stem cell injection on leak point pressure in a rat model of stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct. 2003;14:31–37discussion 7
  15. Cannon TW, Lee JY, Somogyi G, et al. Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra. Urology. 2003;62:958–963
  16. Yokoyama T, Yoshimura N, Dhir R, et al. Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence. J Urol. 2001;165:271–276
  17. Yokoyama T, Huard J, Chancellor MB. Myoblast therapy for stress urinary incontinence and bladder dysfunction. World J Urol. 2000;18:56–61
  18. Kang SB, Lee HN, Lee JY, et al. Sphincter contractility after muscle-derived stem cells autograft into the cryoinjured anal sphincters of rats. Dis Colon Rectum. 2008;51:1367–1373
  19. Falk GW, Fennerty MB, Rothstein RI. AGA Institute medical position statement on the use of endoscopic therapy for gastroesophageal reflux disease. Gastroenterology. 2006;131:1313–1314
  20. Falk GW, Fennerty MB, Rothstein RI. AGA Institute technical review on the use of endoscopic therapy for gastroesophageal reflux disease. Gastroenterology. 2006;131:1315–1336
  21. Crookes PF. Physiology of reflux disease: role of the lower esophageal sphincter. Surg Endosc. 2006;20(suppl 2):S462–S466

 DISCLOSURE: The following authors received research support for this study from Cook Myosite: P. J. Pasricha, I. Ahmed, R. J. Jankowski, M-A. Micci. In addition, the following author disclosed financial relationships relevant to this publication: R. J. Jankowski is an employee of Cook Myosite.

PII: S0016-5107(09)01916-6

doi: 10.1016/j.gie.2009.05.014

Gastrointestinal Endoscopy
Volume 70, Issue 6 , Pages 1231-1237 , December 2009

Article Tools

* Image Usage & Resolution