Gastrointestinal Endoscopy
Volume 71, Issue 1 , Pages 200-204 , January 2010

Trichuris dysentery syndrome: a common cause of chronic iron deficiency anemia in adults in an endemic area (with videos)

  • Mohammad S. Khuroo, MBBS, MD, DM

      Affiliations

    • Corresponding Author InformationReprint requests: Mohammad S. Khuroo, MD, DM, Digestive Disease Centre, Dr. Khuroo's Medical Clinic, Sector 1, Sher-e-Kashmir Colony, Qamarwari, Srinagar, Kashmir, J&K, India 190010.
  • ,
  • Mehnaaz S. Khuroo, MBBS, MD
  • ,
  • Naira S. Khuroo, MBBS

Received 21 June 2009 ,Accepted 6 August 2009.

References 

  1. Bundy D, Cooper E. Trichuris and trichuriasis in humans. Adv Parasitol. 1998;28:107–173
  2. Elliot DE. Intestinal worms. In:  Feldman M,  Friedman LS,  Brandt LJ editor. Sleisenger and Fordtran's gastrointestinal and liver disease: pathophysiology/diagnosis/management. 8th ed. Philadelphia: Elsevier; 2006;p. 2435–2457
  3. Stephenson LS, Holland CV, Cooper ES. The public health significance of Trichuris trichiura. Parasitology. 2000;121:S73–S95
  4. Khuroo MS. Nematodes: ascariasis. Gastroenterol Clin North Am. 1996;25:553–578
  5. Wani SA, Ahmad F, Zargar SA, et al. Intestinal helminths in a population of children from the Kashmir valley, India. J Helminthol. 2008;82:313–317
  6. Bundy DA, Cooper ES, Thompson DE, et al. Predisposition to Trichuris trichiura infection in humans. Epidemiol Infect. 1987;98:65–71
  7. Cooper E, Bundy D. Trichuris is not trivial. Parasitol Today. 1988;4:301–306
  8. Al-Mekhlafi MH, Surin J, Atiya AS, et al. Anaemia and iron deficiency anaemia among aboriginal schoolchildren in rural Peninsular Malaysia: an update on a continuing problem. Trans R Soc Trop Med Hyg. 2008;102:1046–1052
  9. Ramsey F. Trichuris dysentery syndrome. West Indian Med J. 1988;11:235–238
  10. Simeon D, Grantham-McGregor S. Nutritional deficiencies and children's behaviour and mental development. Nutr Res Rev. 1990;3:1–24
  11. Cooper ES, Bundy DA, MacDonald TT, et al. Growth suppression in the Trichuris dysentery syndrome. Eur J Clin Nutr. 1990;44:285–291
  12. Callender J, Grantham-McGregor S, Walker S, et al. Developmental levels and nutritional status of children with the Trichuris dysentery syndrome. Trans R Soc Trop Med Hyg. 1993;87:528–529
  13. Kvalsvig J, Cooppan R, Connolly K. The effects of parasite infection on cognitive processes in children. Ann Trop Med Parasitol. 1991;85:551–568
  14. Cooper ES, Ramdath DD, Whyte-Alleng C, et al. Plasma proteins in children with Trichuris dysentery syndrome. J Clin Pathol. 1997;50:236–240
  15. Duff EM, Anderson NM, Cooper ES. Plasma insulin-like growth factor-1, type 1 procollagen, and serum tumor necrosis factor alpha in children recovering from Trichuris dysentery syndrome. Pediatrics. 1999;103:e69
  16. WHO Expert Committee. Public health significance of intestinal parasitic infections. Prevention and control of intestinal parasitic infections. World Health Organ Tech Rep Ser. 1987;749:8–28
  17. Raj SM. Fecal occult blood testing of Trichuris-infected primary school children in northeastern peninsular Malaysia. Am J Trop Med Hyg. 1999;60:165–166
  18. Taguchi H, Yamamoto H, Miyata T, et al. In vivo diagnosis of whipworm (Trichuris trichiura) with high-definition magnifying colonoscope (with video). Gastrointest Endosc. 2008;68:376–377
  19. Chang CW, Chang WH, Shih SC, et al. Accidental diagnosis of Trichuris trichiura by colonoscopy. Gastrointest Endosc. 2008;68:154
  20. MacDonald TT, Choy MY, Spencer J, et al. Histopathology and immunohistochemistry of the caecum in children with the Trichuris dysentery syndrome. J Clin Pathol. 1991;44:194–199
  21. Cooper ES, Spencer J, Whyte-Alleng CA, et al. Immediate hypersensitivity in colon of children with chronic Trichuris trichiura dysentery. Lancet. 1991;338:1104–1107
  22. Else KJ, Hultner L, Grencis RK. Cellular immune responses to the murine nematode parasite Trichuris muris II. Differential induction of TH-cell subsets in resistant versus susceptible mice. Immunology. 1992;75:232–237
  23. MacDonald TT, Spencer J, Murch SH, et al. Immunoepidemiology of intestinal helminthic infections. 3. Mucosal macrophages and cytokine production in the colon of children with Trichuris trichiura dysentery. Trans R Soc Trop Med Hyg. 1994;88:265–268

 DISCLOSURE: All authors disclosed no financial relationships relevant to this article.

PII: S0016-5107(09)02327-X

doi: 10.1016/j.gie.2009.08.002

Gastrointestinal Endoscopy
Volume 71, Issue 1 , Pages 200-204 , January 2010