Gastrointestinal Endoscopy
Volume 71, Issue 1 , Pages 28-34 , January 2010

Upper GI tract findings in patients with heartburn in whom proton pump inhibitor treatment failed versus those not receiving antireflux treatment

Received 13 May 2009 ,Accepted 23 August 2009.

References 

  1. Fass R, Shapiro M, Dekel R, et al. Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease—where next?. Aliment Pharmacol Ther. 2005;22:79–94
  2. Carlsson R, Dent J, Watts R, et al. Gastro-oesophageal reflux disease in primary care: an international study of different treatment strategies with omeprazole. International GERD Study Group. Eur J Gastroenterol Hepatol. 1998;10:119–124
  3. Inadomi JM, Jamal R, Murata GH, et al. Step-down management of gastroesophageal reflux disease. Gastroenterology. 2001;121:1095–1100
  4. Fass R, Gasiorowska A. Refractory GERD. What is it?. Curr Gastroenterol Rep. 2008;10:252–257
  5. Fass R, Sifrim D. Management of heartburn not responding to proton pump inhibitors. Gut. 2009;58:295–309
  6. Bautista JM, Wong WM, Pulliam G, et al. The value of ambulatory 24 hr esophageal pH monitoring in clinical practice in patients who were referred with persistent gastroesophageal reflux disease (GERD)-related symptoms while on standard dose anti-reflux medications. Dig Dis Sci. 2005;50:1909–1915
  7. Sifrim D, Castell DO, Dent J, et al. Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. Gut. 2004;53:1024–1031
  8. Vela MF, Camacho-Lobato L, Srinivasan R, et al. Simultaneous intraesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: effect of omeprazole. Gastroenterology. 2001;120:1599–1606
  9. Hirano I, Zhang X, Pandolfino JE, et al. Bravo pH capsule monitoring with and without proton pump inhibitor therapy. Clin Gastroenterol Hepatol. 2005;3:1083–1088
  10. Tack J, Koek G, Demedts I, et al. Gastroesophageal reflux disease poorly responsive to single-dose proton pump inhibitors in patients without Barrett's esophagus: acid reflux, bile reflux, or both?. Am J Gastroenterol. 2004;99:981–989
  11. Charbel S, Khandwala F, Vaezi MF. The role of esophageal pH monitoring in symptomatic patients on PPI therapy. Am J Gastroenterol. 2005;100:283–289
  12. Richter JE. How to manage refractory GERD. Nat Clin Pract Gastroenterol Hepatol. 2007;4:658–664
  13. Lichtenstein DR, Cash BD, Davila R, et al. Standards of Practice Committee. Role of endoscopy in the management of GERD. Gastrointest Endosc. 2007;66:219–224
  14. Wo JM, Mendez C, Harrell S, et al. Clinical impact of upper endoscopy in the management of patients with gastroesophageal reflux disease. Am J Gastroenterol. 2004;99:2311–2316
  15. Brazier JE, Harper R, Jones NM, et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305:160–164
  16. Jenkinson C, Coulter A, Wright L. Short form 36 (SF36) health survey questionnaire: normative data for adults of working age. BMJ. 1993;306:1437–1440
  17. Locke GR, Talley NJ, Weaver AL, et al. A new questionnaire for gastroesophageal reflux disease. Mayo Clin Proc. 1994;69:539–547
  18. Lundell LR, Dent J, Bennett JR, et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut. 1999;45:172–180
  19. Sampliner RE. Practice Parameters Committee of the American College of Gastroenterology. Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol. 2002;97:1888–1895
  20. Wakelin DE, Al-Mutawa T, Wendel C, et al. A predictive model for length of Barrett's esophagus with hiatal hernia length and duration of esophageal acid exposure. Gastrointest Endosc. 2003;58:350–355
  21. Gupte AR, Draganov PV. Eosinophilic esophagitis. World J Gastroenterol. 2009;15:17–24
  22. Shaheen NJ, Richter JE. Barrett's oesophagus. Lancet. 2009;373:850–861
  23. Mainie I, Tutuian R, Shay S, et al. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring. Gut. 2006;55:1398–1402
  24. Hirano I, Richter JE. ACG practice guidelines: esophageal reflux testing. Am J Gastroenterol. 2007;102:668–685
  25. Hemmink GJ, Bredenoord AJ, Weusten BL, et al. Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms: ‘on’ or ‘off’ proton pump inhibitor?. Am J Gastroenterol. 2008;103:2446–2453
  26. Peghini PL, Katz PO, Bracy NA, et al. Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors. Am J Gastroenterol. 1998;93:763–767
  27. Orr WC, Harnish MJ. The efficacy of omeprazole twice daily with supplemental H2 blockade at bedtime in the suppression of nocturnal oesophageal and gastric acidity. Aliment Pharmacol Ther. 2003;17:1553–1558
  28. Hetzel DJ, Dent J, Reed WD, et al. Healing and relapse of severe peptic esophagitis after treatment with omeprazole. Gastroenterology. 1988;95:903–912
  29. Gonsalves N, Policarpio-Nicolas M, Zhang Q, et al. Histopathologic variability and endoscopic correlates in adults with eosinophilic esophagitis. Gastrointest Endosc. 2006;64:313–319
  30. Richter JE. The patient with refractory gastroesophageal reflux disease. Dis Esophagus. 2006;19:443–447
  31. Bredenoord AJ, Smout AJ. Refractory gastrooesophageal reflux disease. Eur J Gastroenterol Hepatol. 2008;20:217–223
  32. Wang KK, Sampliner RE. Practice Parameters Committee of the American College of Gastroenterology. Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus. Am J Gastroenterol. 2008;103:788–797

 DISCLOSURE: The following author disclosed financial relationships relevant to this publication: R. Fass: Research support from AstraZeneca; speaker for and research support from Takeda; research support from Wyeth. Research supported by the Office of Research and Development at the Southern Arizona VA Health Care System. All other others disclosed no financial relationships relevant to this publication.

PII: S0016-5107(09)02424-9

doi: 10.1016/j.gie.2009.08.024

Gastrointestinal Endoscopy
Volume 71, Issue 1 , Pages 28-34 , January 2010

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