Gastrointestinal Endoscopy
Volume 72, Issue 3 , Pages 490-496.e1 , September 2010

Biopsy depth after radiofrequency ablation of dysplastic Barrett's esophagus

Received 4 February 2010 ,Accepted 5 April 2010.

References 

  1. Spechler SJ. Clinical practice (Barrett's esophagus). N Engl J Med. 2002;346:836–842
  2. Odze RD, Lauwers GY. Histopathology of Barrett's esophagus 11 after ablation and endoscopic mucosal resection therapy. Endoscopy. 2008;40:1008–1015
  3. Pouw RE, Gondrie JJ, Rygiel AM, et al. Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia. Am J Gastroenterol. 2009;104:1366–1373
  4. Shaheen NJ, Sharma P, Overholt BF, et al. Radiofrequency ablation in Barrett's esophagus with dysplasia. N Engl J Med. 2009;360:2277–2288
  5. Overholt BF, Lightdale CJ, Wang KK, et al. Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett's esophagus: international, partially blinded, randomized phase III trial. Gastrointest Endosc. 2005;62:488–498
  6. Biddlestone LR, Barham CP, Wilkinson SP, et al. The histopathology of treated Barrett's esophagus: squamous reepithelialization after acid suppression and laser and photodynamic therapy. Am J Surg Pathol. 1998;22:239–245
  7. Sharma VK, Wang KK, Overholt BF, et al. Balloon-based, circumferential, endoscopic radiofrequency ablation of Barrett's esophagus: 1-year follow-up of 100 patients. Gastrointest Endosc. 2007;65:185–195
  8. Sharma VK, Kim HJ, Das A, et al. A prospective pilot trial of ablation of Barrett's esophagus with low-grade dysplasia using stepwise circumferential and focal ablation (HALO system). Endoscopy. 2008;40:380–387
  9. Fleischer DE, Overholt BF, Sharma VK, et al. Endoscopic ablation of Barrett's esophagus: a multicenter study with 2.5-year follow-up. Gastrointest Endosc. 2008;68:867–876
  10. Overholt B, Dean PJ, Lightdale CJ. Are biopsies from the neosquamous epithlium (NSE) after photodynamic therapy (PDT) and radiofrequency ablation (RFA) for Barrett's esophagus (BE) comparable in depth to those obtained from untreated squamous epithelium (USE), and, are these biopsies sufficiently deep to detect buried glandular mucosa (BGM) [abstract]?. Gastrointest Endosc. 2009;69:AB343–AB344

 DISCLOSURE: The following authors disclosed financial relationships relevant to this publication: N.J. Shaheen: Research funding from BÂRRX Medical; research funding from and consultant for AstraZeneca; research funding from CSA Medical. B.F. Overholt: Research funding and honoraria from BÂRRX Medical. C.J. Lightdale: Research funding from BÂRRX Medical. A. Chak: Research funding from BÂRRX Medical. K.K. Wang: Research funding from BÂRRX Medical. R.H. Hawes: Research funding from BÂRRX Medical. D.E. Fleischer: Research funding from BÂRRX Medical. J.R. Goldblum: Research funding from BÂRRX Medical. Statistical analysis and data management were supported by National Institutes of Health grants IH P30 DK034987 and T32 DK 07634 (AFP). The other author disclosed no financial relationships relevant to this publication.

PII: S0016-5107(10)01525-7

doi: 10.1016/j.gie.2010.04.010

Gastrointestinal Endoscopy
Volume 72, Issue 3 , Pages 490-496.e1 , September 2010

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