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Original article Clinical endoscopy| Volume 69, ISSUE 6, P1029-1033, May 2009

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Primary incisional therapy with a modified method for patients with benign anastomotic esophageal stricture

  • Tae Hoon Lee
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Suck-Ho Lee
    Correspondence
    Reprint requests: Suck-Ho Lee, MD, Division of Gastroenterology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, 23-20 Bongmyung-dong, Cheonan, Choongnam, Republic of Korea.
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Ji-Young Park
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Chang Kyun Lee
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Il-Kwun Chung
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Hong Soo Kim
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Sang-Heum Park
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Sun-Joo Kim
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Su Jin Hong
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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  • Moon Sung Lee
    Affiliations
    Current affiliations: Division of Gastroenterology, Department of Internal Medicine, (T.H.L., S.-H.L., J.-Y.P., C.K.L., I.-K.C., H.S.K., S.-H.P., S.-J.K.), Soonchunhyang University College of Medicine, Cheonan Hospital (S.J.H., M.S.L.), Cheonan, Bucheon Hospital, Bucheon, South Korea
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Published:February 12, 2009DOI:https://doi.org/10.1016/j.gie.2008.07.018

      Background

      Benign anastomotic esophageal stricture after surgical resection is not uncommon and requires repeated dilation sessions to maintain patency because of the significant recurrence rate with bougie or balloon dilation.

      Objective

      Our study was designed to evaluate whether a modified method of incisional therapy is effective and maintains a good patency in a benign anastomotic esophageal stricture.

      Design

      A prospective outcome study.

      Setting

      Tertiary-care academic medical centers.

      Patients

      A total of 24 patients with benign anastomotic esophageal strictures after esophagojejunostomy.

      Interventions

      Under direct vision through a transparent hood, radial incisions parallel to the longitude of the esophagus were performed by pulling up the Iso-Tome or insulated-tip–knife.

      Main Outcome Measurements

      Efficacy, safety, and long-term patency after procedures were evaluated.

      Results

      During 24 months of follow-up observations, 21 of 24 patients (87.5%) who received only 1 dilation session resumed eating solid meals and had no dysphagia. Only 3 patients (12.5%) developed restricture at a mean of 1.6 months. Of the patients with a recurrence, 2 experienced no recurrence after one additional dilation session, and another patient was refractory and underwent 5 dilation sessions. The occurrence of restricture after incisional therapy was statistically more prevalent in long-segment stricture (>1 cm) (2/3 [66.7%]) than short-segment stricture (<1 cm) (1/21 [4.8%]) (P = .032). There were no significant procedure-related complications.

      Limitation

      Our study included a small number of patients. Therefore, further prospective randomized controlled trials are needed.

      Conclusions

      A modified method of incisional therapy as a primary treatment is safe and feasible, and appears to maintain a longer duration of patency in benign anastomotic esophageal stricture.

      Abbreviation:

      IT-knife (insulated-tip-knife)
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