Traditional endoscopic surveillance of Barrett's esophagus (BE) suffers from a high
rate of sampling error. Angle-resolved low coherence interferometry (a/LCI) is a non-invasive
method of assessing neoplastic tissue. a/LCI obtains nuclear morphology measurements
of epithelial tissues by combining the depth resolution of optical coherence tomography
with the sensitivity to nuclear morphology of light scattering spectroscopy. We report
the results of the first complete clinical in vivo study evaluating the use of a/LCI
to assess BE.
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© 2010 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.