Advertisement

Treatment of Epstein-Barr virus–associated gastric carcinoma with endoscopic submucosal dissection

Published:December 26, 2011DOI:https://doi.org/10.1016/j.gie.2011.09.040
      Epstein-Barr virus (EBV) is a herpes virus that was originally identified in a human Burkitt lymphoma cell line. A small portion of EBV-infected individuals develop hematopoietic, epithelial, and mesenchymal tumors.
      • Yanai H.
      • Nishikawa J.
      • Mizugaki Y.
      • et al.
      Endoscopic and pathologic features of Epstein-Barr virus-associated gastric carcinoma.
      The endoscopic features of EBV-associated gastric carcinoma (EBV-GC) have not been well-documented, and there have been no case reports regarding endoscopic submucosal dissection (ESD). Here, we present a case of EBV-GC that was treated with ESD.

      Abbreviations:

      EBV (Epstein-Barr virus), EBV-GC (EBV-associated gastric cancer), ESD (endoscopic submucosal dissection)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Gastrointestinal Endoscopy
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Yanai H.
        • Nishikawa J.
        • Mizugaki Y.
        • et al.
        Endoscopic and pathologic features of Epstein-Barr virus-associated gastric carcinoma.
        Gastrointest Endosoc. 1997; 45: 236-242
        • Ott G.
        • Kirchner T.H.
        • Muller-Hermelink H.K.
        Monoclonal epithelial malignant cells expressing Epstein-Barr virus genomes but lack of EBV-related protein expression in different types of gastric carcinoma.
        Histopathology. 1994; 25: 323-329
        • Levine P.H.
        • Stemmermann G.
        • Lennette E.T.
        • et al.
        Elevated antibody titers to Epstein-Barr virus prior to the diagnosis of Epstein-Barr virus-associated gastric adenocarcinoma.
        Int J Cancer. 1995; 60: 642-644
        • Nishikawa J.
        • Yanai H.
        • Mizugaki Y.
        • et al.
        Case report: hypoechoic submucosal nodules: a sign of Epstein-Barr virus-associated early gastric cancer.
        J Gastroenterol Hepatol. 1998; 13: 585-590
        • Camargo M.C.
        • Murphy G.
        • Koriyama C.
        • et al.
        Determinants of Epstein-Barr virus-positive gastric cancer: an international pooled analysis.
        Br J Cancer. 2011; 105: 38-43
        • Ojima H.
        • Fukuda T.
        • Nakajima T.
        • et al.
        Discrepancy between clinical and pathological lymph node evaluation in Epstein-Barr virus-associated gastric cancers.
        Anticancer Res. 1996; 16: 3081-3084
        • Takano Y.
        • Kato Y.
        • Saegusa M.
        • et al.
        The role of the Epstein-Barr virus in the oncogenesis of EBV(+) gastric carcinomas.
        Virchows Arch. 1999; 434: 17-22