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Closure methods in submucosal endoscopy

Published:March 28, 2014DOI:https://doi.org/10.1016/j.gie.2014.01.048
      Submucosal endoscopy requires transforming the submucosal layer into an endoscopic working space to allow safe access to the muscularis propria and beyond. The submucosal tunnel places the mucosal incision proximal to the area of interest, thereby simplifying closure to merely mucosal apposition. The earliest clinical adaptation of submucosal endoscopy was peroral endoscopic myotomy for the management of achalasia. More recently, submucosal tunneling endoscopic resection has been demonstrated to be a suitable alternative to surgical removal of tumors originating from the muscularis propria.
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