VideoGIE| Volume 84, ISSUE 6, P1059, December 2016

Download started.


Endoscopic alcohol ablation of solid tumors

      When used for tissue ablation, ethanol induces rapid cell death by means of cell lysis, protein denaturation, and vascular occlusion. Having the benefit of being widely available and cost effective, ethanol is broadly used, with a historical use in interventional gastroenterology for celiac plexus neurolysis. Recently, there has been interest in incorporating alcohol ablation into part of the management algorithm for pancreatic cysts. Isolated case reports describe the application of this technique for the treatment of a variety of solid malignant lesions. However, the scarcity of current published information limits the wider use of this intervention. Here, we describe a series of patients for whom endoscopic alcohol ablation of solid tumors was used as part of a multidisciplinary approach in patients with otherwise difficult-to-treat solid neoplasms. Particular interest is given to describing the technique, measures of therapeutic benefit, and safety profile of this developing skill (Fig. 1; Video 1, available online at
      Figure thumbnail gr1
      Figure 1Endoscopic alcohol ablation of peripheral nerve sheath tumor.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Gastrointestinal Endoscopy
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect