In the operation for Hirschsprung’s disease, an intraoperative pathological diagnosis is necessary to assess the extent of abnormal area of the enteric nervous system (ENS) (aganglionic area). ENS stretches throughout the gastrointestinal tract in a network pattern; therefore, the intraoperative pathological diagnosis evaluating only a small isolated area, is not appropriate to identify the aganglionic area during the surgery.
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© 2017 Published by Elsevier Inc.