Endoscopic hemostasis with through-the-scope clips (TTSC) plus injection therapy is highly effective for bleeding peptic ulcers. However, re-bleeding is difficult to treat and associated with substantial morbidity and mortality. There is growing evidence that application of over-the-scope clips (OTSC) is an effective treatment modality for severe upper gastrointestinal bleeding. Prospective randomized trials are lacking to date.
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© 2017 Published by Elsevier Inc.