Endoscopic quantification of inflammation in ulcerative colitis(UC) is limited to
superficial criteria. Mucosal healing is only validated after 8 weeks of treatment
and therefore cannot predict early therapy response in UC patients undergoing biological
therapy with either anti-integrin or anti-TNF-alpha antibodies. Confocal Laserendomicroscopy(CLE)
allows real-time visualisation of dynamic changes of the mucosal anatomy and might
therefore be a reliable tool for an exact quantification of inflammation in UC.
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© 2019 Published by Elsevier Inc.