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Implications of cannabis use on sedation for endoscopic procedures

      It is well known that recreational substances such as alcohol may have implications on the efficacy and safety of sedation.
      • Yeo H.
      • Kim W.
      • Park H.
      • et al.
      Variables influencing the depth of conscious sedation in plastic surgery: a prospective study.
      • Jeong S.
      • Lee H.G.
      • Kim W.M.
      • et al.
      Increase of paradoxical excitement response during propofol-induced sedation in hazardous and harmful alcohol drinkers.
      However, the literature examining the impact of cannabis use on conscious sedation is sparse. In our experience, two issues have been seen with endoscopy in long-term cannabis users: an increased requirement for sedation, and paradoxic agitation with adjunct anticholinergic medications.

      Abbreviations:

      GABA (gamma-hydroxy-butyrate), THC (Δ9-tetrahydrocannabinol)
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