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Thinking outside the box| Volume 90, ISSUE 4, P656-658, October 2019

Implications of cannabis use on sedation for endoscopic procedures

DOI:https://doi.org/10.1016/j.gie.2019.06.005
Implications of cannabis use on sedation for endoscopic procedures
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      It is well known that recreational substances such as alcohol may have implications on the efficacy and safety of sedation.
      • Yeo H.
      • Kim W.
      • Park H.
      • et al.
      Variables influencing the depth of conscious sedation in plastic surgery: a prospective study.
      Arch Plast Surg. 2017; 44: 5-11
      , 
      • Jeong S.
      • Lee H.G.
      • Kim W.M.
      • et al.
      Increase of paradoxical excitement response during propofol-induced sedation in hazardous and harmful alcohol drinkers.
      Br J Anaesth. 2011; 107: 930-933
      However, the literature examining the impact of cannabis use on conscious sedation is sparse. In our experience, two issues have been seen with endoscopy in long-term cannabis users: an increased requirement for sedation, and paradoxic agitation with adjunct anticholinergic medications.

      Abbreviations:

      GABA (gamma-hydroxy-butyrate), THC (Δ9-tetrahydrocannabinol)
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      Article info

      Identification

      DOI: https://doi.org/10.1016/j.gie.2019.06.005

      Copyright

      © 2019 by the American Society for Gastrointestinal Endoscopy

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