Background and Aims
Abbreviations:CCI (Charlson comorbidity index), CI (confidence interval), CPT (Current Procedural Terminology), GIB (GI bleeding), ICD-9 (International Classification of Diseases Codes), 9th revision (ICD-10), International Classification of Diseases Codes (10th revision), IQR (interquartile range), OR (odds ratio)
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DISCLOSURE: The following authors received research support for this study from the National Institutes of Health: J. X. Yu (2T32 DK 00705642), A. J. Kwong (KL2 TR 001083), and J. L. Lin (KL2 TR 001083 and UL1 TR 001085E). In addition, the following authors disclosed financial relationships relevant to this publication: R. Soetikno: Consultant for Olympus; T. Kaltenbach: Consultant for Olympus and Aries Pharmaceutical. All other authors disclosed no financial relationships relevant to this publication. Research support for this study was provided by a National Institutes of Health National Center for Advancing Translational Science Clinical and Translational Science Award (UL1 TR001085) and internal Stanford funding. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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- What can colonoscopists do now to move management of large benign laterally spreading lesions in the colorectum from surgery to EMR?Gastrointestinal EndoscopyVol. 91Issue 1
- PreviewMost expert colonoscopists in the United States consider EMR to be the first-line treatment for nearly all large (≥20 mm diameter), benign, flat, and sessile colorectal lesions. Flat and sessile lesions >10 mm in diameter are often called laterally spreading lesions (LSLs). The evidence that endoscopic resection is “better” than surgical resection for benign LSLs does not come from randomized controlled trials. Rather, large series show that the mortality, morbidity, and costs of surgical resection are substantially higher than those of EMR,1-3 whereas long-term eradication rates after EMR are very high.