Background and Aim: Endoscopic mucosal resection (EMR) with a cold snare is gaining
increasing acceptance as an effective therapy for large laterally spreading lesions
in the colon. The cold snare technique offers a favorable risk profile, with low rates
of bleeding, perforation, and post-procedure pain compared to the more widely used
hot snare EMR technique. While there is increasing acceptance of cold snare EMR for
the removal of medium (10-19mm) and large (≥20mm) sessile serrated lesions (SSLs),
concerns remain about its suitability for the removal of similar sized adenomas. We
aimed to study the differences in safety and efficacy of cold snare EMR for SSLs as
compared to adenomas at our institution.
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