Esophageal strictures are caused by bands of submucosal fibrous tissue that encroach
upon the lumen and subsequently impede the passage of ingested material from the mouth
to the stomach. In children, esophageal strictures are commonly a result of peptic
esophagitis,
1
ingestion of caustics,
2
or injury at the site of a surgical anastomosis.
3
Current standards of therapy consist of esophageal dilation
4
and, in refractory cases, esophageal resection at the level of stricture.
5
Successful treatment of refractory strictures using intralesional steroid injections
has been reported in a limited number of patients.
6
,
7
,
8
,
9
,
10
We present our experience using endoscopic intralesional steroid injections in seven
patients with refractory esophageal strictures.To read this article in full you will need to make a payment
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References
- The management of peptic esophageal stricture.Br J Surg. 1975; 62: 448-454
- The natural history of liquid lye ingestion: rationale for aggressive surgical approach.Arch Surg. 1974; 109: 436-439
- Gastrointestinal problems in the infant (the esophagus).in: 2nd ed. W.B. Saunders, Philadelphia1983: 170-171
- Balloon dilation of upper digestive tract strictures.Gastroenterology. 1985; 89: 545-548
- Surgical management of peptic esophageal stricture: twenty-year experience.J Thorac Cardiovasc Surg. 1986; 91: 371-378
- The treatment of patients with esophageal strictures by local steroid injections.J Pediatr Surg. 1969; 4: 646-653
- Successful treatment of esophageal strictures without resection or replacement.J Pediatr Surg. 1989; 24: 745-749
- Intralesional steroid injections for peptic esophageal strictures.Gastrointest Endosc. 1991; 37: 180-182
- The treatment of benign strictures of the esophagus with cortisone injection.Ann Otol Rhinol Laryngol. 1970; 79: 900-904
- Intralesional steroids in the treatment of refractory esophageal strictures.J Pediatr Gastroenterol Nutr. 1994; 18: 250-252
- Pathophysiology and management of acute corrosive burns of the esophagus: results of treatment in 285 children.J Pediatr Surg. 1971; 6: 578-584
- Surgical management of reflux strictures of the esophagus in childhood.Ann Surg. 1982; 196: 453-460
- Follow-up on treatment of hypertrophic scars and keloids with triamcinolone.Plast Reconstr Surg. 1971; 48: 256-259
- The treatment of keloids with triamcinolone acetonide.Plast Reconstr Surg. 1966; 38: 202-208
- Keloids treated with topical injections of triamcinolone acetonide (Kenalog).Scand J Plast Reconstr Surg. 1977; 1: 169-172
- Differential glucocorticoid regulation of collagen mRNAs in human dermal fibroblasts. Keloid-derived and fetal fibroblasts are refractory to down-regulation.J Biol Chem. 1989; 264: 13730-13735
- The effect of cortisone on the formation of granulation tissue in mice [Abstract].Am J Pathol. 1950; 26: 710-711
- Intralesional steroid injection in the management of esophageal stricture [Letter].J Pediatr Surg. 1989; 24: 1312
Article info
Publication history
Accepted:
October 24,
1994
Received in revised form:
September 12,
1994
Received:
May 30,
1994
Footnotes
☆From the Department of Pediatrics, Section of Pediatric Gastroenterology, Mayo Clinic and Foundation, Rochester, Minnesota.
☆☆Reprint requests: Jean Perrault, MD, Mayo Clinic, Division of Gastroenterology, 200 First Street S.W., Rochester, MN 55905.
★0016-5107/95/4106-0597$3.00 + 0
★★GASTROINTESTINAL ENDOSCOPY
♢67/69/61468
Identification
Copyright
© 1995 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.
